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The coronavirus disease 2019 (COVID-19) pandemic has had an enormous impact on practically every aspect of daily life, and those with neuromuscular disorders have certainly not been spared. The effects of COVID-19 infection are far-reaching, going well beyond respiratory symptoms alone. From simple myalgias to debilitating critical illness neuromyopathies, we continue to learn and catalog the diverse pathologies presented by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) as it relates to the neuromuscular system. Complications have been documented both as a direct result of primary infection but also in those with pre-existing neuromuscular disorders from myasthenia gravis to devastating critical illness neuromyopathies. In this review, we will discuss the relationship between COVID-19 infection and critical illness neuromyopathy, peripheral nerve palsies, myalgias, positional compressive neuropathy, myasthenia gravis, and Guillain-Barré syndrome.
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This paper reports on the evaluation of an integrated violence and abuse prevention programme for children aged 5–11, focusing on children with special educational needs and disabilities (SEND). The Speak Out Stay Safe (SOSS) programme was delivered in mainstream primary schools across the UK. A small-scale study of children with SEND nested within the larger evaluation captured their understandings of abuse and harm and readiness to seek help. A specially adapted survey was completed by 76 children with SEND (aged 6–7 and 9–10) at baseline (31 intervention;45 comparison schools), 12 in intervention schools post-programme and 37 (four intervention;33 comparison schools) six months post-baseline. Qualitative data was captured through 16 teacher interviews. Whilst this nested study was compromised by the COVID-19 pandemic, it provides important evidence that with appropriate adaptations, a survey approach to investigating the learning of children with SEND can be effective. Findings indicate that awareness of abuse and help seeking strategies may improve over time, whilst interview data suggests that adapting the programme to be inclusive of those children may have a better effect. However, a much larger sample of children with SEND is required to confidently measure the effects of such programmes for this population. © 2023 The Authors. Child Abuse Review published by Association of Child Protection Professionals and John Wiley & Sons Ltd.
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Background: The education of college level badly affected by the Covid-19 because of several reasons. The educational activities of college level are neglected and the education system is becoming unsatisfactory during the deteriorated era of Covid-19. Objectives: The aim of study is to identify the impact of Covid-19 on the academic achievement of student of district Faisalabad. Methodology: Total population will be 267 students of graduation 4th year in the colleges of (Government College for women Karkhana bazar Faisalabad 101, Government Degree College Samanabad 77 and Government postgraduate Islamiya College for women Eidgah road Faisalabad 89). The sample size of this study was 134 (Government college for women karkhana bazar Faisalabad 54, Government degree college Samanabad 38 and Government postgraduate Islamiya college for women Eidgah road Faisalabad 42) by the confidence interval 6% and confidence level 95%.The sample size had been determined by using online available software i.e;www.surveysystem.com. Respondents were selected for research by simple random sampling technique. The data were collected through questionnaire keeping in view the objectives of the study. Collected data were analyzed by using Statistical Package for Social Sciences (SPSS). The respondents of the present study were asked to give their opinion on a five Likert scale. The percentage, mean, standard deviation and rank order were calculated for presents the results. Conclusion: The study was concluded that students were faced numerous social problems due to the spreading of Covid-19 in all over the world. These social problems directly affected the educational system of every country. On the basis of results, it was concluded that the Covid-19 completely deteriorated the educational system and academic achievements of students. So it becomes crucial to reconstruct every fiber of educational society so that development of student’s academic achievement can be enhanced.
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Purpose This study aims to evaluate the impacts of human capital factors in terms of spiritual intelligence (SI), emotional intelligence (EI) and workplace attitude in terms of trust on organizational sustainability (OS) in the hotel industry in Malaysia. In addition, this study intends to examine the mediation role of trust between human capital factors and OS. Design/methodology/approach A survey method using a questionnaire was used to collect data from 361 employees, including middle management, who are in direct contact with guests in the hotel industry. The partial least squares technique, SmartPLS3.3.3, was used to examine the hypotheses. Findings The analysis found support for the impacts of SI, EI and trust on OS. Additionally, the mediation effect of trust was also supported. Originality/value This pioneering study has combined human capital factors (i.e. SI and EI) to predict their effects on OS in the hotel industry. Moreover, this research established relatively new relationships between SI and OS and between EI and OS through the mediation role of trust. Furthermore, this study confirmed the validity and reliability of SI, EI and OS at first and second orders. Given the adverse impact of COVID-19 and its variants on the sustainability of all business organizations, this research has highlighted the crucial role of human factors and workplace attitude in the sustainability of the hospitality sector during difficult times.
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Objective: To evaluate the clinical and laboratory presentation and outcome of COVID-19 patients admitted to a public sector hospital in Pakistan. Methodology: This is a retrospective, cross sectional chart review of COVID-19 patients admitted to Dr. Ruth K.M Pfau Civil Hospital Karachi Isolation Ward from 28th February till May 28th 2020. Results: Out of 306 admitted patients, 216 (70%) tested SARS CoV-2 positive of whom median age was 45. COV-ID-19 was asymptomatic in 35 (16.2%), non-severe in 112 (51.9%), severe in 55 (25.5%) and critical in 14 (6.5%) patients. Severe/critical as compared to asymptomatic/non-severe disease was associated with co-morbidities (37 [53.6%] vs 35 [23.8%], p value <0.001), shortness of breath (50 [72.5%] vs 34 [23.1%], p value <0.001). Median [IQR] values demonstrated lower oxygen saturation (90 [87-92] vs 97 [97-98], p value <0.001) and lower absolute lymphocyte counts (1.3×109/L [0.9-1.82] vs 1.7×109/L [1.1-2.2], p value <0.001) with higher neutrophil to lymphocytic ratio (5.2 [3.3-8.4] vs 2.5 [1.6-3.7], p value <0.001), lactate dehydrogenase level (360U/L [271-566] vs 296U/L [207-377], p value <0.001), C-reactive protein (89mg/L [36-179] vs 19mg/L [0.9-91], p value <0.001) and ferritin level (580mg/L [331-1021] vs 341mg/L [163-679], p value <0.001). Of 216 patients, 2 (0.9%) died in the ward, whereas 13 (6%) were shifted to ICU of whom 12 died. Overall mortality was 14 (6.5%). Conclusion: In COVID-19 patients admitted to a public sector hospital, severe disease was associated with co-morbidities and elevated inflammatory markers. Mortality was very high in those that required ICU care. © 2021, Postgraduate Medical Institute. All rights reserved.
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Introduction: An unusual case of Diffuse Class 4 Lupus Nephritis, along with Collapsing Glomerulopathy from asymptomatic COVID infection Case Description: 42 year old Asian female presented with painless hematuria, anasarca, reduced hearing, and eye redness over a month. She had empiric antibiotics and steroids prior to admission. On admission, she was hypertensive with anasarca. Labs revealed AKI creatinine of 2.5 mg/dl, proteinuria of 11 grams, and serum albumin 1.9 gm/dL. Urine analysis showed dysmorphic RBCs, RBC casts. Ultrasound showed 12 cm kidneys bilaterally. She had normal complements and DS DNA, anticardiolipin and lupus anticoagulant negative. ANA, anticentromere antibody, COVID, PANCA, MPO all positive. Kidney biopsy showed crescentic glomerulonephritis, diffuse proliferative glomerulonephritis Class IV, collapsing glomerulopathy, full house pattern on IF. EM showed sub endothelial, mesangial, and para mesangial deposits, diffuse podocyte foot process effacement, corona virions in endothelial cells. The patient did not have any COVID symptoms and was treated with pulse steroids, MMF induction, hydroxychloroquine, and ACE I. Serum creatinine improved to 1.33 mg/dl, proteinuria improved to 5.6 grams. Her eye redness and hearing impairment resolved. Discussion: This is a rare case of diffuse class IV lupus nephritis with normal complements, DS DNA, and full house pattern on IF. She tested positive for COVID, was asymptomatic, and was able to start treatment. Corona virions and podocytopathy was noted on EM. Improvement in proteinuria, serum creatinine, albumin, and resolution of anasarca were used to monitor response to treatments. Complements and DS DNA could not monitor disease activity. Thus, clinicians should not rely purely on serologies for diagnosis but should pursue kidney biopsy for definitive diagnosis and treatment. Patients may have atypical presentations. (Figure Presented).
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Objective: To find the frequency of stress among gender and to find the association of stress with different factors i.e. city, marital status, occupation, socioeconomic status, body mass index and sleep duration. Methodology: This was an analytical cross-sectional study with a sample size of 553 respondents that was collected through non-probability convenient sampling. Both gender of aged 18-30 years were included in the study. The study was conducted online. Google forms were created and shared among the citizens of Islamabad and Rawalpindi. Frequency of stress among population was measured through Perceived Stress Scale (PSS-10) and self-structured questionnaire was made that includes some variables such as BMI, sleep duration, occupation etc. Data was analyzed using SPSS version 21. Results: Out of 553 participants, 343(62%) were female and 210(38%) male. Mean age was 22.42 +/- 2.91 years. Mean of PSS score was 19.16 +/- 5.8. Most had moderate level of stress. There was an association of stress with gender (p<0.005), while no association was found with other variables (BMI, sleep duration and occupation (p>0.005). Conclusion: Most of the participants had moderate level of stress which was more on in females. There was an association of stress with gender while no association was found with BMI, sleep duration and occupation.
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Information and Communications Technology (ICT) has revolutionized the healthcare leading to provision of eHealth facilities remotely. During the peak time of COVID-19, as the long queues at health care facilities can result in spread of the virus. ICT can play an effective role especially for reducing the extended waiting time of patients to consult a medical practitioner which is considered as a source of hazard during the pandemic. However, in developing countries where majority population is semiliterate so find difficulty when come into contact with appointment systems which are not particularly designed keeping in consideration the requirements of semiliterate users. It is extremely important to better understand how to design user interface which allow semiliterate users to effectively perform the tasks. So there is a dire need to develop a simple, effective, easy to learn user interface (UI) of an online appointment system for the productive doctor-patient consultation. Therefore, this study aimed to providing an effective user interface of web based online appointment system to semi-literate users through User-Centered Design (UCD) methodology. To achieve this, a prototype was designed to overcome issues in the existing appointment systems gathered through a field study. The needs and expectation for semiliterate users were fulfilled by incorporating the requirements of UI development for the target users. A sample of forty-two semiliterate users was used to evaluate the prototype. The evaluation results showed that semiliterate users’ performance measured using— effectiveness, efficiency and satisfaction significantly improved while interacting with the prototype as compared to existing interfaces. The effectiveness is measured through number of errors and tasks accomplished in UI, efficiency by the time required to complete the task and satisfaction by System Usability Scale (SUS). The SUS score improved from 50.8 to 77.6 for the prototype. © 2021, Tech Science Press. All rights reserved.